Survival of HIV/AIDS patients with antiretroviral therapy initiated in 2005-2020:an analysis based on data from Fengtai District of Beijing
Objective To study the status and associated factors of survival in patients with antiretroviral therapy(ART)initiated in 2005-2020 for human immunodeficiency virus/acquired immunodeficiency syndrome(HIV/AIDS)in Fengtai District of Beijing.Methods A retrospective cohort study was conducted on the follow-up data of patients with ART initia-ted from 2005 to 2020 in Fengtai District collected from the National HIV/AIDS Comprehensive Control and Prevention In-formation System.The life table method was used to calculate the survival rate.Cox proportional hazards regression model was employed to explore associated factors of survival time.Results A total number of 3 417 cases were enrolled.In total,there was 40 HIV/AIDS-related deaths.The cumulative survival rate of patients at 1,3,5,10,and 15 years after ART was 99.24％,99.02％,98.83％,97.05％,and 97.05％,respectively.Multivariate analysis using Cox proportional hazards model revealed that the risk of death was higher in patients aged ≥50 years than that in those aged 15-29 years(HR=3.46,95％CI:1.00-11.90),and was higher in patients with baseline CD4+lymphocyte count＜200 cells/pl than in those with baseline CD4+lymphocyte count≥500 cells/pl(HR=12.71,95％CI:1.70-95.25).Conclusion The survival rate is relatively high in the study population.To further reduce HIV/AIDS related mortality,early detection and treatment,and monitoring of treatment effect should be continuously strengthened,and high-level attention should be paid to patients of ol-der age.
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