Analysis of the Disease Burden and Trend of Osteoporosis in China from 1990 to 2021
Objective:To analyze the disease burden and trend of osteoporosis in China from 1990 to 2021,and provide theoretical basis for the prevention and control of osteoporosis. Methods:Using the Global Burden of Disease 2021 (GBD 2021) database,the descriptive analysis of the mortality and disease burden of osteoporosis in different sex and age groups in China from 1990 to 2021 was conducted,the annual change percentage and the average annual change percentage were calculated using Joinpoint Software,and the Age-Period-Cohort (APC) model was used to evaluate the impact of age,period and birth cohort factors on disease burden. Results:The mortality and disease burden of Low Bone Mineral Density (LBMD) in male is higher than that of female,and the mortality and disease burden increases with age,and the mortality and disease burden is the highest in people over 80 years old. The gross rate of Disability Adjusted Life Years (DALYs) in female is higher than that in male after the age of 65;falls are the leading cause of LBMD-related deaths. The mortality rate,DALY rate and YLL rate showe a downward trend. The burden of LBMD mortality and disease in China is higher than that in the world. The age effect coefficient shows an upward trend,the period effect coefficient shows a first increasing and then decreasing trend,and the birth cohort effect coefficient shows a downward trend. Conclusion:With the intensification of aging,the burden of osteoporosis-related diseases in China will still be very heavy in the future. It is needed to actively carried out fall prevention and control strategies to reduce the occurrence of osteoporotic fractures and related deaths;take multiple measures to strengthen the monitoring and prevention of osteoporosis.
disease burdenosteoporosisAge-Period-Cohort (APC) Model
万方数据
维普
