Objective Human T lymphotropic virus (HTLV-Ⅰ / Ⅱ) is a kind of complex retrovirus and widely distributed throughout world.The corresponding information was reported in local area of China.This paper aims to investigate the infection status of human T lymphotropic virus among volunteer blood donors in Sheyang,and provide appropriate strategies for blood safety in this area.Methods HTLV-Ⅰ / Ⅱ antibody was detected in blood donors in Shenyang area by home-made double antigen sandwich ELISA kit in the first test.The positive blood samples in the first test were re-tested by double-hole retrial method.Then the seropositive samples were confirmed by RT-PCR or Western blot.Results A total of 9050 voluntary blood donors were detected from March to May in 2013,5 samples were suspected positive,but confirmed negative with RT-PCR or WB,the false positive rate was 0.06％.Conclusion The blood donors belong to the low-incidence and non-epidemic area of HTLV-Ⅰ / Ⅱ infection in Shenyang.Based on the analysis of the blood test cost and transfusion safety,leucodepletion treatment may be better to prevent the HTLV-Ⅰ / Ⅱ virus infection in blood transfusion.
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