Risk factors for nosocomial infections with carbapenem-resistant Serratia marcescens
Objective This paper aims to explore the risk factors for nosocomial infections with carbapenem-resistant Serratia marcescens(CR-SMA),so as to provide theoretical basis for the prevention and control of nosocomial infections with CR-SMA.Methods Thirty-eight patients with CR-SMA nosocomial infections treated from Jan.2016 to Dec.2022 were select-ed as the CR-SMA group,and thirty-eight patients associated with carbapenem-sensitive Serratia marcescens(CS-SMA)were selected at a ratio of 1∶1 and assigned as the CS-SMA group.The clinical characteristics and the usage of antibiotics of the two groups were statistically analyzed.The risk factors for nosocomial infections with CR-SMA were analyzed by univariate and multivariate logistic regression analysis.Results Univariate sensitivity analysis showed that the length of hospitalization stay before SMA infection≥14 d,diabetes,other bacterial infections,the time of antibiotics before CR-SMA infection≥14 d and the use of ventilator(P＜0.05).Multivariate logistic regression analysis showed that the use of ventilator and the time of antibiotics before CR-SMA infection≥ 14 d were independent risk factors for nosocomial infection of CR-SMA(P＜0.05).Conclusion Clinical attention should be paid to the use of ventilators and antibiotics for long duration.High-risk groups should be regularly monitored,aseptic operations should be strengthened,disinfection and isolation measures should be imple-mented,and antibiotics should be standardized to reduce the occurrence of nosocomial infections and prevent the spread of drug-resistant bacteria in hospitals.
NETL
NSTL
万方数据
维普
