首页|1 243例住院儿童常见呼吸道病原体检测情况分析

1 243例住院儿童常见呼吸道病原体检测情况分析

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目的 探讨湖州地区儿童常见呼吸道病原体的流行特征.方法 收集2021年12月-2022年11月呼吸道感染住院患儿的标本共1 243例,采用PCR毛细电泳片段分析法检测常见的13种呼吸道病原体,并对结果进行统计分析.结果 1 243例标本病原体检出率为63.80%(793/1 243).单一病原体以HRV、HRSV、HPIV、MP和HMPV检出率较高,分别为15.45%、10.22%、7.08%、5.07%和4.67%;≥2种病原体以HPIV+HRV和HRV+HRSV检出率较高,分别为1.37%和1.13%.流感病毒中InfA检出率为4.18%,InfB检出率为3.46%,其中48例InfA是H3N2型,未检出H1N1型.男、女童病原体检出率分别为64.22%和63.19%,差异无统计学意义(P>0.05).年龄0个月~6个月组、>6个月~1岁组、>1岁~3岁组和>3岁组病原体检出率分别为60.39%、66.25%、71.10%和60.43%,差异有统计学意义(P<0.05).冬季、春季、夏季和秋季病原体检出率分别为72.75%、58.99%、56.37%和65.63%,差异有统计学意义(P<0.05).结论 湖州市儿童呼吸道感染以HRV、HRSV和HPIV等病毒为主,流行高峰在秋冬季,学龄前儿童检出率较高.
Detection and analysis of common respiratory pathogens in 1 243 hospitalized children
Objective This paper aims to explore the epidemiological characteristics of common respiratory pathogens in children in Huzhou area.Methods A total of 1 243 pathogenic samples of hospitalized children with respiratory tract infections were collected from December 2021 to November 2022.PCR capillary electrophoresis fragment analysis was used to detect 13 common respiratory pathogens,and the results were analyzed statistically.Results The detection rate of pathogens in 1 243 specimens was 63.80%(793/1 243).The detection rates of single pathogens were high in HRV,HRSV,HPIV,MP,and HMPV,respectively with 15.45%,10.22%,7.08%,4.99%,and 4.67%.The detection rates of HPIV+HRV and HRV+HRSV were high among ≥2 pathogen-causing infections,which were respectively 1.37%and 1.13%.The detection rate of InfA in influenza virus was 4.18%,while the detection rate of InfB was 3.46%.Among them,48 cases of InfA were H3N2 type and no H1N1 type was detected.The incidence rates of male and female pathogen examinations were 64.22%and 63.19%,with the differences not statistically significant(P>0.05).The detection rates of pathogen in the 0-6 month group,the6month-1 year group,the 1-3 year group,and the 3-year group were respectively 60.39%,66.25%,71.10%,and 60.43%,with the differences statistically significant between the groups(P<0.05).The incidence rates of pathogenic bacteri-a in winter,spring,summer,and autumn were respectively 72.75%,58.99%,56.37%,and 65.63%,with the differences statistically significant(P<0.05).Conclusion The respiratory tract infections in children in Huzhou City are mainly caused by viruses such as HRV,HRSV,and HPIV,with a peak prevalence in autumn and winter and a high detection rate among pre-school children.

Respiratory tract infectionPathogenChildren

李云、沈国松、杨帆、闵晶、李刚

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湖州市妇幼保健院检验科,浙江 313000

呼吸道感染 病原体 儿童

湖州市公益性应用研究项目

2020GY16

2023

中国卫生检验杂志
中华预防医学会

中国卫生检验杂志

影响因子:0.771
ISSN:1004-8685
年,卷(期):2023.33(22)
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