首页|基于血清白蛋白的老年营养风险指数对社区绝经后女性群体骨质疏松症的早期预警价值

基于血清白蛋白的老年营养风险指数对社区绝经后女性群体骨质疏松症的早期预警价值

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目的 探讨基于血清白蛋白的老年营养风险指数(GNRI)对社区绝经后女性群体骨质疏松症的早期预警价值.方法 纳入2022年1月一 12月在温州市中医院-温州市水心社区卫生服务中心医联体治疗的所辖社区298例绝经后老年女性的临床资料,分为骨质疏松组100例和非骨质疏松组198例.比较2组一般资料及骨代谢指标之间的差异,分析GNRI与骨密度之间的相关性,探讨GNRI与骨质疏松的关系并评估GNRI对骨质疏松症的早期预警价值.结果 骨质疏松组绝经年限高于非骨质疏松组,而血清白蛋白、GNRI以及平均骨密度均低于非骨质疏松组,差异均有统计学意义(P<0.05).随着GNRI营养风险等级下降,骨质疏松症构成比呈下降趋势(P<0.01).校正年龄、BMI和绝经年限后GNRI仍与白蛋白(r=0.540,P<0.05)和平均骨密度(r=0.609,P<0.05)成正相关关系.多因素logistic回归显示GNRI与骨质疏松的发生成负相关关系,是骨质疏松症发生的独立保护因素(P<0.05).结论 在社区绝经后女性群体中,GNRI与骨质疏松的发生密切相关,高GNRI水平是绝经后女性骨质疏松发生的独立保护因素;GNRI是有效的骨质疏松症早期预警指标,在绝经年限超过10年的女性群体中GNRI的预警效能较优.
The early warning value of serum albumin-based geriatric nutritional risk index for osteoporosis in postmenopausal women of community
Objective This study aims to explore the early warning value of serum albumin-based geriatric nutritional risk index(GNRI)for osteoporosis in postmenopausal women of community.Methods The clinical data of 298 postmenopausal female patients in the communities in the jurisdiction of Wenzhou Traditional Chinese Medicine Hospital-Wenzhou Shuixin Community Health Service Center Medical Association from January 2022 to December 2022 were included and divided into the osteoporosis group(100 cases)and the non-osteoporosis group(198 cases).The differences of general data and bone metabo-lism indexes between the two groups were compared,the correlation between GNRI and bone mineral density was analyzed,the relationship between GNRI and osteoporosis was discussed,and the early warning value of GNRI for osteoporosis was evaluated.Results The osteoporosis group had higher menopausal years than the non-osteoporosis group,while serum albumin level,GNRI scores and mean bone mineral density were lower than the non-osteoporosis group,with the differences statistically sig-nificant(P<0.05).With GNRI grade decreasing,the osteoporosis composition ratio decreased simultaneously(P<0.01).After corrected for age,BMI and years of menopause,GNRI was still positively associated with albumin(r=0.540,P<0.05)and mean bone mineral density(r=0.609,P<0.05).Multivariate logistic regression showed that GNRI was negatively associ-ated with the osteoporosis and was an independent protective factor for the osteoporosis(P<0.05).Conclusion In the postm-enopausal women of these communities,GNRI is closely related with the occurrence of osteoporosis,and high GNRI levels are an independent protective factor for the occurrence of osteoporosis.GNRI is an effective early warning indicator for osteoporosis.The early warning efficacy of GNRI is better in women with menopause over 10 years.

Geriatric nutritional risk indexOsteoporosisPost-menopauseCommunityFemaleEarly warning

朱烈烈、叶晓林、余丽飞、邵湘芝、吴登宠、翁雷

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温州市中医院康复科,浙江 325000

温州市鹿城区松台街道水心社区卫生服务中心康复综合医学科

老年营养风险指数 骨质疏松症 绝经后 社区 女性 预警

温州市科协服务科技创新项目

jczc153

2023

中国卫生检验杂志
中华预防医学会

中国卫生检验杂志

影响因子:0.771
ISSN:1004-8685
年,卷(期):2023.33(23)
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