Clinical effect of Wenxin Granule in adjuvant therapy of patients with acute coronary syndrome and its influence on ischemic J wave,brain natriuretic peptide and inflammatory factors
Objective This paper aims to investigate the clinical effect of Wenxin Granule in the adjuvant treatment of acute coronary syndrome and its influence on ischemic J wave,brain natriuretic peptide(BNP)and inflammatory factors.Methods Retrospective analysis was performed on 104 patients with acute coronary syndrome admitted to our hospital from January 2021 to January 2023,who were divided into observation group(53 cases)and control group(51 cases)by random method.The control group was treated with conventional western medicine,and the observation group was treated with Wenxin Granule on the basis of control group.The treatment courses were both 3 months.The changes of various indexes before and after treatment were compared between the two groups.Results The total effective rate of the observation group(90.57％)was higher than that of the control group(70.59％),and the difference was statistically significant(P＜0.05).The incidence of ischemic J wave decreased in both groups after treatment(P＜0.05).The incidence of ischemic J wave in the observation group was lower than that in the control group(x2=4.735,P＜0.05).Serum hs-CRP and MMP-9 levels decreased in both groups after treatment(P＜0.05).The serum hs-CRP and MMP-9 levels in the observation group were lower than those in the control group(P＜0.05).Plasma BNP levels decreased in both groups after treatment(P＜0.05).The plasma BNP level of the observation group was lower than that of the control group after treatment(t=13.748,P＜0.05).No obvious adverse reactions was observed in both groups.Conclusion The adjuvant treatment of Wenxin Granule in patients with acute coronary syndrome has significant clinical effect,and can reduce the occurrence of ischemic J wave and the level of BNP and inflammatory factors,which is worthy of clinical reference.
NETL
NSTL
万方数据
维普
