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脊柱术后手术部位感染病原菌分布及危险因素调查

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目的 了解脊柱手术部位感染(SSI)病原菌的分布及其感染的危险因素,为感染防控措施的实施提供依据.方法 通过回顾性分析方法,对某医院住院实行脊柱手术治疗的患者术后手术部位感染病原菌检测结果进行统计分析.结果 共调查2 148例脊柱手术患者,发生术后手术部位感染72例,感染率为3.35%.脊柱手术部位感染的发生率从2019年的4.38%下降至2022年的1.34%.从切口分泌物中共分离到病原菌78株,其中革兰阳性菌占66.67%,革兰阴性菌占29.49%,居前3位的病原菌分别是金黄色葡萄球菌、表皮葡萄球菌和大肠埃希菌.耐甲氧西林金黄色葡萄球菌检出率为21.74%,耐甲氧西林表皮葡萄球菌检出率为60.00%,未检测出对万古霉素耐药的菌株.大肠埃希菌对亚胺培南耐药率为0.00%.多因素分析显示,糖尿病、再次入院、同种异体输血、夏季等因素为脊柱手术部位感染的独立危险因素(P<0.05).结论 脊柱手术切口感染病原菌主要以金黄色葡萄球菌为主,感染危险因素明确,有针对性的防控措施可有效预防手术切口感染.
Pathogenic bacteria distribution in surgical site infection after spinal surgery and investigation of risk factors
Objective This paper aims to investigate the distribution of pathogenic bacteria and the risk factors of infection in spinal surgical site,so as to provide evidence for infection prevention and control measures.Methods Retrospective analysis was performed on the pathogenic bacteria detection results of postoperative incision infection in patients undergoing spinal surger-y in a hospital.Results A total of 2 148 spinal surgery patients were investigated,72 cases of postoperative incision infection were observed,and the infection rate was 3.35%.The incidence of spinal surgical site infections decreased from 4.38%in 2019 to 1.34%in 2022.A total of 78 strains of pathogenic bacteria were isolated from incision secretions,of which 66.67%were Gram-positive and 29.49%were Gram-negative.The top 3 pathogenic bacteria were Staphylococcus aureus,Staphylo-coccus epidermidis and Escherichia coli.The detection rate of methicillin-resistant Staphylococcus aureus(MRSA)was 21.74%,and that of methicillin-resistant Staphylococcus epidermidis was 60.00%.No vancomycin resistant strains was detec-ted.The resistance rate of Escherichia coli to imipenem was 0.00%.Multivariate analysis showed that diabetes,readmitted to hospital,alloblood transfusion and summer were independent risk factors for spinal surgical site infection(P<0.05).Conclu-sion Staphylococcus aureus is the main pathogen of incision infection in spinal surgery,the risk factors of infection are clear,and targeted prevention and control measures can effectively prevent incision infection.

SpinalSurgical site infectionPathogenic bacteriaDrug resistanceRisk factor

徐彩娃、孙永宁

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浙江省永康市妇幼保健院,浙江 321300

宁波市第六医院

脊柱 手术部位感染 病原菌 耐药性 危险因素

2023

中国卫生检验杂志
中华预防医学会

中国卫生检验杂志

影响因子:0.771
ISSN:1004-8685
年,卷(期):2023.33(23)
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