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肠道菌群与代谢研究进展

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从出生伊始肠道菌群就依赖于宿主的基因组、营养和生活方式而变化的,与宿主共同进化发展.肠道菌群参与调控其宿主的多种代谢途径,包括宿主的免疫、营养,并且极大地影响宿主的物质能量代谢及与物质能量代谢相关疾病的发生与发展过程.同时又与多个器官共同作用,在宿主的代谢、信息传递,疾病的感染与防御方面起非常重要的作用.深入了解肠道菌群在其参与代谢的具体作用,对理解物质能量代谢相关疾病病因、优化治疗策略、调节肠道菌群、防治疾病和提高宿主健康水平具有重要作用.本研究对人类肠道菌群的形成、物质能量代谢、代谢相关疾病及其防治等方面的研究进展加以综述.
Progress in researches on gut microbiota and metabolism
The gut microbiota depends on the host's genome, nutrition and life-style from birth and co-evolutes with the host. The intestinal flora regulates a variety of metabolic pathways of host, including the host's immune and nutrition, and greatly affects the host's biochemical metabolism and susceptibility to diseases. Together with multiple organs, it plays an important role in the metabolism, signalling and combating diseases. Understanding the specific role of the gut microbiota in their participation in various metabolic activities is very important to optimize treatment strategies, regulate the intestinal flora, combat diseases and improve health. The formation of the human intestinal flora, material and energy metabolism, metabolic diseases and research progress of the prevention and treatment of these diseases were summarized in this paper.

Gut microbiotaMetabolismTreatment strategies

刘银辉、唐立

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大连医科大学微生态学教研室,辽宁大连 116044

肠道菌群 代谢 防治

2013

中国微生态学杂志
中华预防医学会 大连医科大学

中国微生态学杂志

CSTPCDCSCD
影响因子:1.115
ISSN:1005-376X
年,卷(期):2013.25(3)
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