Distribution of microbiota and related infection factors in amniotic cavity infection
Objective To observe the distribution of amniotic fluid microbiota,related infection factors and infection symptoms in postpartum women during cesarean section,providing a reference for the treatment.Methods A total of 498 amniotic fluid samples from our hospital during cesarean section from June 2020 to February 2023 were collected for bac-terial culture.Based on the distribution of microbiota in amniotic fluid and the related factors,clinical infection symptoms were comprehensively analyzed.Results In the 498 amniotic fluid samples,147 samples were microorganisms positive,with a total detection rate of 29.5％(147/498).Among the 498 postpartum women,100 had preoperative infection symp-toms,and 78 strains of microorganisms were detected;51 cases showed postoperative infection symptoms and 34 strains of microorganisms were detected;8 cases of postoperative incision infection and 7 strains of microorganisms were detected;28 out of 339 postpartum women without clinical infection symptoms were found to be microorganisms positive.The de-tection rate of microorganisms was related to premature rupture of membranes or artificial rupture of membranes after trial delivery,the distribution of vaginal microbiota,and the occurrence of infection symptoms before surgery(all P＜0.05).Conclusion For high-risk pregnant women with premature rupture of membranes and dysbiosis of vaginal microbiota,timely detection of pathogens can provide an effective reference for early prevention and targeted treatment of amniotic cavity infection.
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