Research progress on vaginal flora in children and adolescent girls
Women's vaginal flora is closely related to diseases.Because of differences in the levels of estrogen,the vagin-al flora of children and adolescents differs from that of reproductive women.The diversity of vaginal flora of prepubertal girls is high,the dominant bacteria are anaerobic bacteria,and the count of lactobacilli is low.Adolescent vaginal flora has changed before menarche,with the dominant bacteria having become lactobacilli.After menarche,the composition of flora is similar to that of reproductive women.As for the pathogens of vulvovaginitis,there are also differences between chil-dren/adolescents and reproductive women.Streptococcus pyogenes,Haemophilus influenzae,Staphylococcus aureus and Escherichia coli are common pathogens in prepubertal patients.Candida albicans shows the highest infection rate in puber-tal patients.Deeply understanding the characteristics of the vaginal flora in healthy and vulvovaginitis children and adoles-cents is conducive to timely detection,diagnosis and treatment of reproductive tract diseases in children and adolescents.