Correlation between energy expenditure and gut microbiota among females in college
Objective To observe the characteristics of energy expenditure and gut microbiota of young and middle-aged women in colleges,and analyze the correlation between different energy consumption indicators and potential biomarkers.Methods Energy consumption monitoring was conducted among young college women(Y group,n=30)and middle-aged women(M group,n=30)who wore physical activity energy consumption detectors for 48 hours.Statistical analysis was performed to determine the differences in daily energy expenditure among different groups.The gut microbiota was subjected to 16S rRNA gene sequencing and bioinformatics analysis to identify potential biomarkers.Correlation tests and regression analysis were carried out at order and genus levels between potential biomarkers and energy consumption indic-ators.Results Statistically significant differences were observed in body consumption(step counts/d,kcals/d,MVPA time/d)between Y group and M group.At the order and genus levels,there were abundance differences mainly in Lactoba-cillales(t=2.537,P=0.014),Dialister(t=2.904,P=0.005),and Blautia(t=3.246,P=0.002).Additionally,Lactobacillales and Dialister showed positive correlations with energy consumption indicators,while Blautia showed a negative correlation.Conclusion Energy consumption metrics such as step counts/d,kcals/d,and MVPA time/d are associated with better physical functioning.Under specific circumstances,increasing the duration of ligh-,moderate-and vigorous-intensity activ-ity time may enhance the abundance of Lactobacillales and Dialister,thereby retarding the decline of body functions.
Gut microbiomeEnergy expenditurePhysical activityFemaleCorrelation
NETL
NSTL
万方数据
