摘要
全球乙型肝炎病毒感染者人数众多,如未进行及时、有效的治疗,慢性乙型肝炎往往会发展为肝硬化、肝细胞癌和肝衰竭等.随着对肠道微生态的逐渐关注和肠-肝轴概念的提出,研究人员发现慢性乙型肝炎、肝硬化、肝细胞癌和肝衰竭患者的肠道微生态往往具有不同的特征,进而探讨肠道微生态与慢性乙型肝炎、肝硬化、肝细胞癌和肝衰竭等乙型肝炎相关慢性肝病的发生发展、诊断和治疗之间的关系,以期能更有效地使用肠道微生态技术.本文主要从上述乙型肝炎相关慢性肝病着手,总结肠道微生态在相关疾病中作用的最新研究进展.
Abstract
There are a large number of people infected with hepatitis B virus in the world.Without timely and effective treatment,patients with chronic hepatitis B tend to progress to cirrhosis,hepatocellular carcinoma,liver failure and other stages.With the gradual attention to intestinal microecology and the proposal of the concept of intestinal-liver axis,re-searchers found that the intestinal microecology of patients with chronic hepatitis B,cirrhosis,hepatocellular carcinoma and liver failure often had different characteristics,and then explored the relationship between intestinal microecology and the occurrence,development,diagnosis and treatment of hepatitis B related chronic liver diseases such as chronic hepatitis B,cirrhosis,hepatocellular carcinoma and liver failure.It is hoped that intestinal microecological techniques can be used more effectively.This article mainly focuses on the above hepatitis B related chronic liver disease,and summarizes the latest progress in research on intestinal microecology in related diseases.
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