摘要
目的 分析近20年国际上艰难梭菌相关性腹泻(CDAD)的研究现状与热点.方法 检索WebofSci-ence数据库2003年1月1日至2023年12月31日期间收录的相关文献,应用CiteSpace 6.2.R6软件对发文量、作者、国家、机构、被引文献、被引期刊及关键词等进行可视化分析.结果 共检索出文献13 495篇,近20年全球发文量稳步递增,美国(6480篇)在该领域发表的文献最多.发文量最大的机构是美国退伍军人事务部(645篇),Wilcox(137篇)是成果产出最多的作者,被引频次最多的期刊是Clinical Infection Dis-ease(9 257 次).该领域的高频关键词是"Clostridium difficile""infection""Clostridium difficile infection",关键词聚类可大致分为4个方向:risk factors、Clostridium difficile、Vancomycin和diarrhea,研究热点主要集中在CDAD的患病率、危险因素及治疗措施方面.结论 近20年CDAD的研究越来越受到学者们的重视,未来研究可更多围绕着CDAD安全、有效、经济的治疗措施展开.
Abstract
Objective To analyze the status and hot spots of research on Clostridium difficile-associated diarrhea(CDAD)internationally over the past two decades.Methods The related literatures collected in the Web of Science data-base from January 1,2003,to December 31,2023 were retrieved and the number of publications,authors,journals,related disciplines,countries,institutions and keywords were visually analyzed based on Citespace 6.2.R6.Results A total of 13,495 papers were retrieved.The global volume of publications had showed an overall upward trend in the last 20 years,with the United States(6,480 articles)publishing the most publications in this field.The US Department of Veterans Af-fairs was the most prolific institution,publishing 645 articles,and Wilcox was the most productive author with 137 publica-tions.The most cited journal was the Clinical Infection Disease(9,257 times).The keywords with high frequency were"Clostridium difficile","infection"and"Clostridium difficile infection".The keyword clustering could be roughly divided into four directions:risk factors,Clostridium difficile,Vancomycin and diarrhea.The research focus was mainly on the pre-valence,risk factors and treatment measures of CDAD.Conclusion Over the past two decades,the research on CDAD has been paid more and more attention by scholars,and the future research may focus more on safe,effective and econom-ical treatment measures for CDAD.
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