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中药益生元的研究进展

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中药是我国传统医学的重要组成部分,具有悠久的历史背景和丰富的临床应用基础。随着现代医学的不断发展,中药在预防和治疗肠道疾病方面显示出独特的优势,但其作用机制尚待阐明。近年来,随着对肠道菌群的深入研究,人们逐渐认识到中药中的有些成分具有益生元的作用,且与传统的益生元相比,具有特殊的药理活性和天然来源的优势。因此,本文就党参、黄芪、人参和枸杞等单体中药以及复方制剂的益生元作用作一综述,以期为中药益生元的研究和临床开发提供参考。
Prebiotics in Chinese materia medica:research progress
Chinese materia medica constitutes a significant component of our country's traditional medical practices,boasting an extensive historical background and rich clinical applications.With the continuous evolution of modem medi-cine,Chinese materia medica has demonstrated unique advantages in both the prevention and treatment of intestinal dis-orders.However,the precise mechanisms of its actions remain to be fully elucidated.In recent years,as a result of in-depth research into the gut microbiota,there has been a gradual recognition that certain components within Chinese materia medica possess prebiotic effects,promoting a healthy gut microbiota.Moreover,these components exhibit distinctive phar-macological activities and originate from natural sources,setting them apart from traditional prebiotics.Hence,this article aims to provide a comprehensive review of the prebiotic effects found in individual components of Chinese materia medica such as Codonopsis pilosula,Astragalus membranaceus,Panax ginseng,Lycium barbarum,and compound formulations.The objective is to serve as a reference for the research and clinical development of prebiotics derived from Chinese mater-ia medica.

Chinese materia medicaPrebioticsGut microbiota

邵匡振、丁向萍、张子恒、傅思武

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西北民族大学医学部,甘肃兰州 730030

中药 益生元 肠道菌群

西北民族大学中央高校创新团队项目

31920200025

2024

中国微生态学杂志
中华预防医学会 大连医科大学

中国微生态学杂志

CSTPCD北大核心
影响因子:1.115
ISSN:1005-376X
年,卷(期):2024.36(7)