Intestinal microbiota and liver regeneration:progress in research
The liver is a powerful regenerative organ and the regenerative process is regulated by several factors.After partial hepatectomy and liver transplantation,the ability of the liver to return to normal form and function is critical to the success of the procedure.Therefore,identifying the factors that regulate liver regeneration plays a crucial role in promoting liver regeneration.It has been found that the large and complex intestinal microbiota and its metabolites play a significant role in liver regeneration,among which intestinal endotoxemias,bile acids associated with intestinal microbiota and intest-inal bacterial metabolites,such as short-chain fatty acids and tryptophan metabolites,are involved in liver regeneration.However,the exact mechanism is not clear.In this paper,we review the progress in research on intestinal microbiota and its metabolites and liver regeneration to provide a reference for clinical work and related research.
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