Gut microbiota are closely related to mitochondria of intestinal epithelial cells in many aspects such as source,function and structure.Gut microbiota and their metabolites can affect the function of mitochondria in intestinal epithelial cells by regulating energy metabolism.Meanwhile,mitochondria of intestinal epithelial cells also influence the abundance and distribution of gut microbiota.The interaction between gut microbiota and mitochondria of intestinal epithelial cells is mainly reflected in two aspects:reactive oxygen species(ROS)level and Ca2+homeostasis.This article focuses on the new progress in research on ROS level and Ca2+homeostasis in the interaction between gut microbiota and mitochondria of in-testinal epithelial cells,so as to provide reference for clinical targeted regulation of gut microbiota and mitochondria of in-testinal epithelial cells to regulate intestinal function and improve related diseases.
关键词
肠道菌群/肠道上皮细胞线粒体/相互作用/活性氧/Ca2+稳态
Key words
Gut microbiota/Mitochondria of intestinal epithelial cells/Interaction/Reactive oxygen species/Ca2+homeo-stasis
维普
万方数据