Strenthening and balancing effects of Astragalus in treatment of diabetic kidney disease based on intestinal microecology:research progress
The intestinal microecological environment plays an indispensable role in the occurrence and development of diabetic kidney disease.Astragalus is one of the commonly used drugs in the clinical treatment of diabetic kidney disease,which can not only upregulate the richness of the unbalanced flora,but also maintain the intestinal barrier function.For ex-ample,if the harmful flora and the derivatives it produced due to the imbalance of intestinal flora are regarded as"evil qi",and the intestinal epithelial barrier,as well as the intestinal energy metabolism and immune function are regarded as"vital qi",then the evil prosperity and positive energy deficiency are the main reasons for the further damage of kidney in diabet-ic patients due to the destruction of intestinal microecology.With astragalus,the traditional Chinese medicine,as the treat-ment means and intestinal flora as the link,the"drug-bacteria-human"trinity dynamic adjustment mechanism is formed in order to make diabetic kidney disease patients achieve a status of the balance and coexistence of human and bacteria as well as good and evil.Therefore,based on microecology,this paper discusses the mechanism of astragalus in repairing the in-testinal epithelial barrier,improving its immunity to'fuzheng",regulating the stability of intestinal microecological envir-onment to"adjust the balance",and then treating and delaying diabetic kidney disease,in hope to provide new ideas and theoretical basis for clinical treatment.
Diabetic kidney diseaseIntestinal microecologyAstragalusFuzheng and adjust the balance
万方数据
维普
