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益生菌科学共识和应用指南概述

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目前,益生菌越来越被科学界和消费者认可。随着对益生菌的研究不断增多,大部分国家和地区的科学组织都对益生菌提出过相关的科学共识和应用指南,但是这在全球范围内并没有统一。为了引导益生菌产业健康发展,让益生菌在促进人民健康中发挥更好的作用,本文旨在系统总结目前一些主要国家和团体组织对益生菌的科学共识和应用指南,以期为营养卫生工作者和消费者提供科学可行的应用指南。现有的科学共识和应用指南大多数是针对特定的健康问题提出使用特定益生菌菌株的建议,其中有5种健康问题被2个及以上的应用指南或科学共识推荐使用益生菌,并提及了干预剂量与时间,这些健康问题包括急性胃肠炎、抗生素相关性腹泻、院内感染腹泻、婴幼儿肠绞痛和坏死性小肠结肠炎。然而,要系统地广泛使用益生菌,仍需要更多高质量研究的支持。
Overview of scientific consensus and practical guidelines for probiotics
At present,probiotics are increasingly recognized by the scientific community and consumers.With the in-creasing research on probiotics,scientific organizations in most countries and regions have put forward relevant scientific consensus and practical guidelines for probiotics,which,however,is not uniform on a global scale.In order to guide healthy industrial development and protect consumer interests,this paper aims to systematically summarize the current con-sensus and practical guidelines of probiotics in major countries and organizations,and provide scientific and feasible prac-tical guidelines for nutrition and health providers and consumers.Most of the existing practical guidelines and scientific consensus suggest the use of specific probiotic strains in selected conditions.Five of the conditions are recommended by two or more practical guidelines or scientific consensus with mentioning the dose and timing of interventions,including acute gastroenteritis,antibiotic-associated diarrhea,nosocomial infection diarrhea,infantile colic,and necrotizing entero-colitis.However,more high-quality studies are still needed to support the systematic and widespread use of probiotics.

Scientific consensusProbioticsPractical guidelines

刘斐童、陆泽荣、张施琦、陈咏春、胡瑞标

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健合集团研究与创新中心,广东广州 510700

华南理工大学食品科学与工程学院

合生元(广州)健康产品有限公司

科学共识 益生菌 应用指南

2024

中国微生态学杂志
中华预防医学会 大连医科大学

中国微生态学杂志

CSTPCD北大核心
影响因子:1.115
ISSN:1005-376X
年,卷(期):2024.36(8)