婴幼儿口咽部微生态研究进展
Oropharyngeal microecology in infants and young children:advance in research
王丽敏 1王瑞晔 1杨慕涵 1王婧 1杨占双1
作者信息
- 1. 佳木斯大学,黑龙江佳木斯 154000
- 折叠
摘要
婴幼儿时期是免疫发育的关键时期,对维持人体健康具有重要作用.婴幼儿时期也是口咽部微生物定植和演替的关键时期,受分娩方式和喂养选择的强烈影响,最终形成微生态平衡.口咽部微生物之间及其与宿主之间的相互作用,在口咽部免疫的发育中起着重要作用,并与多种呼吸道疾病的发生发展密切相关.对婴幼儿口咽部微生态的研究表明,在定植的"窗口期",主要微生物群的差异与长大后的呼吸道疾病有关.本文将分别从婴幼儿母乳喂养与免疫发育、口咽部微生物群定植与演替以及口咽部微生态系统等方面进行综述.
Abstract
The infancy and early childhood are a critical period for immune development and play an important role in maintaining human health.Infancy is also a critical period for oropharyngeal microbial colonization and succession,which is strongly influenced by delivery mode and feeding choice,and ultimately forms a dynamic ecological balance of microor-ganisms.The interactions between oropharyngeal microorganisms and their host play an important role in the development of oropharyngeal immunity,and are closely related to the occurrence and development of various respiratory diseases.Studies on the oropharyngeal microecology of infants and young children have shown that the differences in major micro-bial communities during the"window period"of colonization are associated with respiratory diseases later in life.In this paper we reviews infant breastfeeding and immune development,oropharyngeal microbiome colonization and succession,and oropharyngeal microecosystem.
关键词
口咽部/微生态/微生物群/婴幼儿Key words
Oropharynx/Microecology/Microbiome/Infant引用本文复制引用
出版年
2024
NETL
NSTL
万方数据