Objective To summarize the best practice evidence of management and prevention of drug administra-tion errors in children,and provide reference for clinical drug use.Methods Evidence-based questions were construc-ted according to the problem development tool of JBI Evidence-Based Health Care Center in Australia.Guidelines and consensus related to medication errors were searched.The quality of the included literatures was evaluated by research-ers,and the literatures meeting the quality standards were extracted and summarized.Results A total of 9 literatures were included,including 2 guidelines and 7 expert consensus articles.Finally,a total of 34 best evidences were summa-rized from the aspects of management,environment and equipment,labeling,information,verification,medical advice,administration,high-risk drug management,etc.Conclusion The evidence for prevention of drug administration er-rors in children is comprehensive,and the quality of inclusion guidelines is relatively high,but the guidelines for pediatric population are insufficient,and the prevention of drug administration errors in children is more important than the pre-vention of dose errors.In the future,more research on prevention strategies for drug administration errors should be car-ried out.