Strengthening the construction of disciplines is an important starting point for improving the core com-petitiveness of hospitals.By systematically combing the relevant policy documents of discipline construction,based on the SWOT analysis method,this paper analyzed the discipline construction of a large tertiary general hospital in western Chi-na from four aspects:advantages,disadvantages,challenges and opportunities,summed up the achievements of disci-pline construction in recent years,put forward key measures and strategies to promote discipline construction,and pro-vided reference for laying out discipline development planning,drawing discipline construction blueprints,and realizing leapfrog development of disciplines.