Summary of Best Evidence for the Prevention and Control Management of Bloodstream Infections Associated with Central Venous Cathe-ters for Blood Purification
Objective To retrieve,evaluate and summarize the evidence of prevention and control management of bloodstream infection related to central venous catheter for blood purification,and provide evidence-based basis for he-modialysis care.Methods According to the"6 S"evidence model,clinical practice guidelines,expert consensus,sys-tematic review,evidence summary and best clinical practice for the prevention and control of bloodstream infections re-lated to central venous catheters for blood purification were systematically searched in databases and websites.The search period was up to July 25,2023.Literature quality evaluation,evidence extraction,analysis and integration were conduc-ted by two researchers.Results A total of 16 studies were included,including 8 guidelines,5 expert consensus,and 3 systematic reviews.Forty-one pieces of best evidence were summarized from 7 aspects of risk factors and system man-agement,sterile barrier,catheter indwelling,catheter assessment,catheter maintenance,and flushing and sealing tube management.Conclusion In the process of evidence transformation,medical staff should apply the evidence according to the catheter retention time and individual differences of patients,and timely update the relevant evidence to reduce the incidence of bloodstream infections associated with central venous catheters for blood purification.