Objective To analyze the rationality of clinical application of antibiotics in operation group of monitoring network in China.Methods The reasonableness of the use of antibiotics in the operation group was evaluated by estab-lishing the case evaluation criteria of the clinical application monitoring network of antibiotics.Results The use of pre-ventive antibiotics in the surgical group showed a decreasing trend.In 2021,the use of preventive antibiotics in Class I in-cision surgery was 32.20%,and the rate of use without indication decreased from 11.35%in 2017 to 6.87%in 2021.The rationalization rate of antimicrobial use increased from 15.05%in 2017 to 29.73%in 2021.Irrational manifestations were mainly irrational drug use in perioperative period,with an average composition ratio of 55.13%in 5 years,followed by ir-rational drug selection,with an average composition ratio of 18.58%in 5 years,and unreasonable daily administration times and single dose.Conclusion It is necessary to strengthen the management and monitoring of antibiotic use in operation to ensure the safety of clinical use.
Antibacterial DrugRational Drug UseDrug Use EvaluationPerioperative PeriodMonitoring