Objective To optimize the treatment process of PCI supported by extracorporeal membrane oxygena-tion(ECMO)in patients with acute myocardial infarction complicated by cardiogenic shock based on the Hammer-process reengineering model,and to shorten the first medical contact to balloon(FMC-To-B).Methods Through the establishment of a process reengineering management team,combing the original process,analyzing the proportion of non-value-added time in each link of the process,formulating process improvement plans,including the develop-ment of mobile PDA,moving forward or moving backward the operations accumulated in the emergency department,es-tablishing a multi-disciplinary collaboration mechanism,strengthening the training of treatment teams,and establis-hing a multi-sectoral collaborative supervision mechanism.Results After the process reengineering,FMC-first ECG time,FMC-multi-disciplinary remote consultation time,FMC-intervention opening time,FMC-ECMO place-ment completion time,FMC-To-B time were shorter than before the process reengineering.Conclusion The re-engineered treatment process can effectively shorten the FMC-To-B time,improve the medical quality.