首页|颅脑损伤患者深静脉血栓危险因素的Meta分析

颅脑损伤患者深静脉血栓危险因素的Meta分析

Meta-Analysis of Risk Factors for Deep Venous Thrombosis in Patients with Traumatic Brain Injury

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目的 探讨颅脑损伤(TBI)患者深静脉血栓(DVT)的危险因素,为预防TBI患者发生DVT提供依据.方法 利用计算机检索中英文数据库中关于TBI患者DVT发生危险因素的相关文献,检索时限为建库至2024年1月14日,由两位研究者筛选文献、提取资料并进行质量评价.结果 共纳入14篇文献,Meta分析结果显示,年龄≥50岁、BMI>30 kg/m2、GCS≤8分、糖尿病、高血压、呼吸机支持>4 d、住院总天数≥15 d、深静脉置管、凝血酶原时间短、D-二聚体升高是TBI患者发生DVT的危险因素(P<0.05).结论 TBI患者发生DVT的危险因素较多.医护人员需落实规范化DVT风险评估,关注高风险患者,采取针对性预防措施,如定期监测凝血指标、合理使用抗凝药物、鼓励早期下床活动、优化呼吸机使用策略及严格遵循无菌操作规范等;同时应构建TBI患者DVT风险预测模型,以有效降低DVT发生风险,提高患者预后和生活质量.
Objective To investigate the risk factors of deep venous thrombosis(DVT)in patients with traumatic brain injury(TBI),and to provide evidence for the prevention of DVT in patients with TBI.Methods The relevant literatures on the risk factors of DVT in patients with TBI were retrieved by computer from Chinese and English databas-es.The retrieval time was from the establishment of the database to January 14,2024.Two researchers screened the lit-erature,extracted the data and evaluated the quality.Results A total of 14 articles were included.Meta-analysis re-sults showed that age≥50 years old,BMI>30 kg/m2,GCS≤8 points,diabetes,hypertension,ventilator support>4 d,total hospitalization days≥15 d,deep vein catheterization,short prothrombin time,and elevated D-dimer were risk factors for DVT in TBI patients(P<0.05).Conclusion There are many risk factors for DVT in TBI pa-tients.Medical staff should implement standardized DVT risk assessment,pay attention to high-risk patients,and take targeted preventive measures,such as regular monitoring of coagulation indicators,rational use of anticoagulants,en-couragement of early ambulation,optimization of ventilator use strategies,and strict compliance with aseptic operation specifications.At the same time,medical institutions should construct a DVT risk prediction model for TBI patients so as to effectively reduce the risk of DVT and improve the prognosis and quality of life of patients.

Traumatic Brain InjuryDeep Venous ThrombosisRisk FactorsMeta-AnalysisNursing Quality

高雅、刘晓楠、李晶、易晓平、王文爽

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首都医科大学附属北京天坛医院 北京 100070

颅脑损伤 深静脉血栓 危险因素 Meta分析 护理质量

首都医科大学附属北京天坛医院院青年护理专项

2022-YQN-06

2024

中国卫生质量管理
中国医院协会,陕西省人民医院

中国卫生质量管理

CSTPCD
影响因子:1.091
ISSN:1006-7515
年,卷(期):2024.31(10)