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神经电生理监测引导下脊髓电刺激植入术治疗糖尿病高危足患者

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目的 分析神经电生理监测下全麻一次性脊髓电刺激器植入术治疗糖尿病高危足患者的临床效果.方法 收集 2022 年 5 月至 2023 年 5 月于天津市环湖医院神经外科九病区行脊髓电刺激植入术的 7 例糖尿病高危足患者的临床资料.手术在"C"型臂X线引导和神经电生理监测下进行,全麻一次性植入脊髓电刺激器.比较患者术前与术后下肢动脉直径和峰值流速、下肢皮肤温度(小腿皮温、足部皮温)、视觉模拟量表(VAS)评分、持续行动距离、血糖水平及足趾创面情况.结果 共纳入 7 例糖尿病高危足患者.患者术后双下肢股动脉、腘动脉、胫前动脉、胫后动脉和足背动脉直径、峰值流速均较术前明显改善.7 例患者术前均存在不同程度下肢疼痛感,术后VAS评分明显下降(分:1.1±0.9 比 6.8±3.4),疼痛明显缓解,且小腿皮温和足部皮温均较术前明显升高[小腿皮温(℃):33.3±0.9 比 30.9±0.7,足部皮温(℃):31.4±0.8 比 29.1±0.6],空腹血糖和餐后血糖均较术前明显降低[空腹血糖(mmol/L):7.6±1.4 比 10.5±1.2,餐后血糖(mmol/L):9.3±2.3比 13.5±1.1],差异均有统计学意义(均P<0.01).全部 7 例患者术后下肢活动较术前明显改善,其中 1 例术前需轮椅出行、1 例术前存在间歇性跛行,术后 2 周患者均恢复正常行走.7 例患者中,2 例患者术前糖尿病足伤口溃烂,长期不能愈合,术后 1 个月患者足部伤口周围血运恢复,加速愈合,伤口周围干燥、结痂,愈合良好.结论 对不耐受糖尿病周围神经痛及局麻脊髓电刺激测试的糖尿病高危足患者进行神经电生理监测下全麻一次性植入脊髓电刺激器,能够有效缓解周围神经痛和其他糖尿病足相关症状,改善下肢血流供应,并降低足趾截肢风险.临床实践证实该技术方法有效性,尤其对于糖尿病高危足患者早期治疗效果显著.
Spinal cord electrical stimulation with neurophysiological monitoring for treatment of high-risk diabetic foot
Objective To evaluate the clinical efficacy of a single-session implantation of spinal cord electrical stimulation with neurophysiological monitoring a spinal cord electrical stimulator under general anesthesia with neurophysiological monitoring for the treatment of high-risk diabetic foot.Methods The clinical data of seven patients with high-risk diabetic foot who underwent spinal cord electrical stimulation in neurosurgery ward nine of Tianjin Huanhu Hospital from May 2022 to May 2023 were collected.The operation was performed under general anesthesia with the"C"arm X ray machine guidance and neurophysiological monitoring.The arterial diameter and peak flow rate of lower extremity,lower extremity skin temperature(calf skin temperature,foot skin temperature),visual analog scale(VAS),continuous distance of movement,blood glucose level and toe wound were compared between patients before and after surgery.Results A total of seven patients with high-risk diabetic foot were included.The diameters and peak flow rates of femoral artery,popliteal artery,anterior tibial artery,posterior tibial artery and dorsal foot artery in both lower limbs were significantly improved after surgery.All patients had different degrees of lower limb pain before operation.After operation,VAS score decreased significantly(1.1±0.9 vs.6.8±3.4),the pain was significantly relieved,and the calf skin temperature and foot skin temperature were significantly higher than those before surgery[calf skin temperature(℃):33.3±0.9 vs.30.9±0.7,foot skin temperature(℃):31.4±0.8 vs.29.1±0.6],fasting blood glucose and postprandial blood glucose were significantly lower than those before surgery[fasting blood glucose(mmol/L):7.6±1.4 vs.10.5±1.2,postprandial blood glucose(mmol/L):9.3±2.3 vs.13.5±1.1],the differences were statistically significant(all P<0.01).The lower limb movement of all seven patients was significantly improved after surgery,including one patient who needed wheelchair travel before surgery,and one patient who had intermittent claudication before surgery.Among them,one patient needed wheelchair travel and one patient had intermittent claudication before surgery.All patients could walk normally at 2 weeks after operation.Among the seven patients,two patients had the diabetic foot wound ulceration before surgery,which could not heal for a long time.One month after surgery,blood flow around the foot wound recovered and the healing was accelerated.The wound was dry and crusted around the wound,and the wound healed well.Conclusion For diabetic high-risk foot patients who are intolerant to diabetic peripheral neuralgia and local anesthesia spinal cord electrical stimulation test,one-time implantation of spinal cord electrical stimulator under general anesthesia under neurophysiological monitoring can effectively alleviate peripheral neuralgia and other diabetic foot related symptoms,improve lower limb blood supply,and reduce the risk of toe amputation.Clinical practice has proved the effectiveness of this technique,especially for the early treatment of diabetic high-risk foot patients.

Spinal cord electrical stimulationDiabetic footNerve regulationNeurophysiological monitoring

李志涛、黎文汉、尹绍雅、刘宝龙、秦楠、刘鑫

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天津市环湖医院神经外科,天津 300350

天津市环湖医院超声科,天津 300350

天津市环湖医院神经电生理科,天津 300350

脊髓电刺激植入术 糖尿病足 神经调控 术中神经电生理监测

2024

中华危重病急救医学
中华医学会

中华危重病急救医学

CSTPCD北大核心
影响因子:3.049
ISSN:2095-4352
年,卷(期):2024.36(3)
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