Relationship between sporadic pre-excitation syndrome and PRKAG2 gene polymorphism
Objective To explore the relationship between sporadic pre-excitation syndrome and PRKAG2 gene polymorphism. Methods Genomic DNA was isolated from peripheral lymphocytes obtained from 65 patients with sporadic pre-excitation syndrome and 65 normal persons. Mutation analysis was performed using purified Polymerase chain reaction(PCR) products to direct sequence analysis on PRKAG2. Results No mutation was identified in the 65 patients and 65 normal persons. Conclusion There is no relationship between PRKAG2 gene polymorphism and sporadic pre-excitation syndrome.