An analysis of pathogens and drug sensitivity of neonatal septicemia
Objective To explore pathogens characteristics isolated from neonates with septicemia and analyze their drug sensitivity. Methods The results of blood culture and drug susceptibility test for 285 neonatal patients with septicemia treated in our hospital were analyzed. Results Out of the blood samples, 285 stains were detected with a result of Gram positive (245strains) accounting for 86. 0% and Gram negative (40 strains) accounting for 14. 0%. 87 strains Staphylococcus epidermidis 30. 5% , 49 strains Staphylococcus haemolyticus 17. 2% , 24 strains Staphylo-coccus simulans 8. 4%, 21 strains Staphylococcus aureus 7. 4% , 18 strains Escherichia coli 6. 3 % were the five most common pathogens. Gram positive cocci demonstrated a strong resistance to penicillin (90. 0%), oxacillin (74.7%), erythromycin(74. 3%) and ampicillin(71. 4%) , and was susceptible to vancomycin and nitrofurantoin. The resistance of Gram negative bacilli to ampicillin(72. 5%) was high, and their susceptibility to cefoperazone/ sul-bactam.imipenem and meropenem was evident. Conclusions Much more attention should be paid to drug resistance detection in the treant of neonatal septicemia. Choosing sensitive antibiotics based on the drug sensitivity tests may decrease the occurrence of drug resistant bacteria and increase the clinical curative effects.
NETL
NSTL
万方数据
维普
