首页|胸腔积液中Survivin和CEA联合检测对肺癌的诊断价值

胸腔积液中Survivin和CEA联合检测对肺癌的诊断价值

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  • NETL
  • NSTL
  • 万方数据
  • 维普
目的 评价联合检测Survivin和癌胚抗原(CEA)对肺癌诊断价值.方法 检测77例肺癌患者和72例良性胸腔积液患者胸腔积液中Survivin和CEA水平,应用ROC曲线评价诊断效能.结果 Survivin和CEA在最优截断点的灵敏度分别为80.5％和71.4％,特异度分别为86.1％和84.7％；平行试验灵敏度和特异度为94.4％和72.9％；系列试验灵敏度和特异度为57.5％和97.8％.结论 联合检测胸腔积液Survivin和CEA对肺癌诊断价值优于单独检测.
Diagnostic value of survivin and CEA in pleural effusion in detecting lung cancer
Objective To evaluate the diagnostic value of survivin and CEA in pleural effusion (PE) in detecting lung cancer. Methods CEA and survivin in PE were measured in 77 patients with malignant PE and 72 patients with benign PE. To evaluate diagnostic value of CEA and survivin by receiver operating characteristic (ROC) curve. Results At the optimum cut-off value, survivin and CEA of sensitivity were 80. 5% and 71. I% , and their specificity were 86. 1% and 84. 7%, respectively. Sensitivity and specificity in parallel tests were 94. 4% and 72. 9%, and were 57. 5% and 97. 8% in serial tests. Conclusions Combined assay of survivin and CEA seems to be better than survivin or CEA alone to diagnose lung cancer.

Microtubule-Associated Proteins/AnalysisNeoplasm Proteins/AnalysisCarcinoembryonic Antigen/AnalysisPleural Effusion/metabolismLung Neoplasms/diagnosis

孔虹、张晓平、刘勇

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中国医科大学附属盛京医院检验科,辽宁沈阳110003

微管相关蛋白质类/分析 肿瘤蛋白质类/分析 癌胚抗原/分析 胸腔积液/代谢 肺肿瘤/诊断

2012

中国误诊学杂志
中华预防医学会　漯河市中心医院　重庆第九人民医院

中国误诊学杂志

影响因子：0.406
ISSN：1009-6647
年,卷(期)：2012.12(8)
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