Non-psammomatous melanotic schwannoma of sacral canal:a case report and literature review
Objectives To investigate the clinicopathological features, diagnosis and differential diagnosis of non-psammomatous melanotic schwannoma (NPMS), and to improve its diagnostic level. Methods The features of his-topathology were observed by means of HE stains in 1 case of NPMS as well as literature review. Results Microscopically, NPMS was composed of fusiform shape and oval epithelioid tumor cells, the melanin granule was found in most tumor celb which covered up the nucleus of the tumor cells. Tumor cystic degeneration was found, but the necrosis and pathological mitotic figure wasn't observed. Conclusions NPMS is a rare peripheral nerve tumor, characterized by distinctive histopathologieal features and often confused with other pigment soft tumors. Although most of the NPMS are benign, a few have the potential of malignant change. The long-term follow-up should be stressed after operation.