骶管非砂粒体型黑色素性神经鞘瘤1例报告并文献复习
Non-psammomatous melanotic schwannoma of sacral canal:a case report and literature review
徐文漭 1李霞 2杨丽琳 1王媛媛 1李涛 1王力 1黎贵芸1
作者信息
- 1. 成都军区昆明总医院病理科,云南昆明650032
- 2. 成都军区昆明总医院全军骨科中心,云南昆明650032
- 折叠
摘要
目的 探讨非砂粒体型黑色素性神经鞘瘤(NPMS)的临床病理特点、诊断及鉴别诊断要点,提高病理医生对NPMS的认识及诊断水平.方法 应用HE染色对1例发生于骶管的NPMS进行组织形态学观察,并复习相关文献.结果 光镜下NPMS由长形及卵圆形上皮样瘤细胞组成,多数瘤细胞胞质内可见黑色素颗粒并将细胞核掩盖.肿()变,但无坏死,未见病理性核分裂象.结论 NPMS是一种罕见的周围神经肿瘤,具有特征性的组织病理学特点,易与其他含有色素的软组织肿瘤混淆.多数NPMS为良性,少数病例会恶变,术后应长期随访复查.
Abstract
Objectives To investigate the clinicopathological features, diagnosis and differential diagnosis of non-psammomatous melanotic schwannoma (NPMS), and to improve its diagnostic level. Methods The features of his-topathology were observed by means of HE stains in 1 case of NPMS as well as literature review. Results Microscopically, NPMS was composed of fusiform shape and oval epithelioid tumor cells, the melanin granule was found in most tumor celb which covered up the nucleus of the tumor cells. Tumor cystic degeneration was found, but the necrosis and pathological mitotic figure wasn't observed. Conclusions NPMS is a rare peripheral nerve tumor, characterized by distinctive histopathologieal features and often confused with other pigment soft tumors. Although most of the NPMS are benign, a few have the potential of malignant change. The long-term follow-up should be stressed after operation.
关键词
黑色素瘤/病理学/诊断/神经鞘瘤/病理学/诊断/诊断,鉴别/病例报告Key words
Melanoma/pathology/Neurilemmoma/pathology/Diagnosis, Differential/Case Reports引用本文复制引用
出版年
2012
NETL
NSTL
维普
万方数据