A study of the precautionary application of antibiotics in clean surgical operations by Clinical Pharmacist
Objective To evaluate and analysis the effect of the application and intervention of antibiotics in clean surgical operations during penoperative period in a top three hospital. Methods We extract discharged 324 cases before the intervention from June of 2009 to May of 2010 and 420 cases after the intervention from June of 2010 to May of 2011, then we analysis the situation about the precautionary application of antibiotics of all the clean surgical cases. Results We found antibiotics were used in 324 clean surgical cases before the intervention ,use ratio is 100%; antibiotics were used in 50 cases (15. i%) 0. 5~2 hours before operations; 64 cases (19. 8%) were given antibiotics 2 ~24 hours before operations. 185 cases(64. 8%) received antibiotics after operations and average medication time after operations is 5. 34days. We found 198 cases (47. 177) use no antibiotics among 420 cases after the intervention, antibiotics were used in 28 cases (6. 7%) 0. 5~2 hours before operations; 22 cases (5. 2%) were given antibiotics after operations and average medication time after operations is 1. 44 days, We found infection ratio have no difference before and after intervention. Conclusions We find great improvement in irrationnal phenomenons about the precautionary application of antibiotics in clean surgical operations (types of I incision) after the intervention,but we still have a gap in the use ratio (the requirement of Ministry of Health is<30% )of the precautionary application of antibiotics in clean surgical operations (types of I incision). We need to strengthen management and training of standardized application of antibiotics in surgeons to ensure the application of antibiotics is safe, effective and economic.
NETL
NSTL
万方数据
维普
