Expression and significance of uPA and P-P38 in primary hepatocellular carcinoma
Objective To determine the expression of Upa and P-P38 in hepatocellular carcinoma and its significance. Methods 34 cases of hepatocellular cancer, 14 cases of normal endometrial tissue were detected in uPA and P-P38 by immunohisto chemistry S-P. Results The expressions of uPA and P-P38 were located with the endometrial and the cytoplasm. Their expressions were higher than the normal tissue(P<0. OS). Both of them were related with myometrial invasion .lymph nodemetastasis, clinical stage and pathological staging( P<0. OS). The results of comparing with each other were positive correlation between them(P<0. 05). Conclusion Upa and P-P38 are highly expressed in hepatocellulat cancinoma and their expressions are related with hepatocellular carcinoma the development and the metastasis.
Liver NeoplasmsmetabolismPlasminogen Activatorsmetabolismp38 Mitogen-Activated Protein Kinasesmetabolism