Effecct of Dioscornin tablets in carotid atherosclerosis
Objective To investigate the effects of the Dioscornin tablets) DCT) on the expression of carotid artery in-tima- mediathickness(IMT) in patients with carotid atherosclerosis. Method Seventy-nine patients with carotid atherosclerosis were randomly divided treatment group and control group. Treatment group given conventional treatment and Dioscornin tablets!DCT). Control group given conventional treatment. All patients were followed up with using high frequency ultrasound and color Doppler ultrasound measuring IMT and the parameters of lipid and hemo-rheology before treatment and after 6 months and 1 year. Result After 1 year, the carotid IMT of treatment group treatmented by DCT was significicantly thinner(P<0. 05) .the serum total cholesterol,triglycerides decreased sig-nificicantly(P<0.05) .HDL-C was significicamly higher(P<0. 05). The carotid IMT,blood lipids(TC,TG,LDL-C) of the control group showed no significicant difference after treatment. Conclusion DCT is an effective drug to treatment atherosclerosis.