Study of relationship between expression of VEGF-D and lymph metastasis in tongue squamous cell carcinoma
Objective To detect the expression levels of VEGF-D(vascular endothelial growth factor-D) in tongue squamous cell carcinoma. To analyse the possible mechanism of the VEGF-D of lymph node metastasis in tongue squamous cell carcinoma. Methods To research the expression of proteinum of VEGF-D in 69 cases of tongue squamous cell carcinoma by use oC immunohistochemistry of PV9000. Results The positive expression of VEGF-D in tongue squamous cell carcinoma was 43.48%. There was statistical difference of the positive expression rate of control group(P>0.05). The positive rate of VEGF-D in lymph node metastasis group were higher than those of non lymph node metastasis group(.P>0. 05). Conclusion The high expressive rate of VEGF-D proteinum is associated with lymph node metastasis.
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