Clinical value on NSE and S-100B of serum in children with hand-foot-mouth diseases combined with viral encephalitis
Objective To detect the expresions of NSE and S-100B of serum in children with hand-foot-mouth diseases compbined with viral encephalitis, and investigate their clinical significance. Methods 62 children with hand-foot-mouth diseases compbined with viral encephalitis were observed as observation group, 50 children with hand-foot-mouth which eliminated central nerous system disease were observed as control group,50 normal children were observed as normal control group. The expressions of NSE and S-100B were detected in the three groups. Results The expressions of NSE and S-100B were obviously higher in the observation group than in the other groups. The expressions of NSE and S-100B were obviously correlated with convulsion in the observation group. There were positively correlated between NSE and S-100B in the observation group. Conclusion The higher expressions of NSE and S-100B can induce the development of hand-foot-mouth diseases compbined with viral encephalitis. The combined examination of NSE and S-100B may be helpful to predict the pathological degree in hand-foot-mouth diseases.
Hand, Foot and Mouth DiseasecomplicationsEncephalitis, ViralcomplicationsPhosphopyruvate HydratasemetabolismNerve Growth FactorsmetabolismS100 Proteinsmetabolism
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