Study on relationship between NT-BNP and cardioversion of patient with heart failure combined with atrial fibrillation
Objective Before cardioversion with Amiodarone in patient with heart failure) HF) combined with atrial fi-brillation( AF) ,to make a study about the predictive value of NT-pro BNP level for cardioversion effect. Methods To observe the level changes of NT-pro BNP of 150 patients with HF combined with AF between before and after cardioversion with intravenous Amiodarone 5-7 mg/kg, dropping over with in 30 to 60 minutes. Result After 150 cases with paroxysmal taking drug,within 48 hours,100 paticnts(66. 67%) converted sinus rhythm,before cardioversion, plasma NT-pro BNP level about successful cardioerter groups was (967. 04±366.16) ng/L,obviously lower than unsuccessfully cardioerter group! 1 182.04±298. 34) ng/L(P<0. 01),after cardioversion for 1 hour,plasma NT-pro BNP level of successful cardioerter groups was (496. 21 ± 142. 54) ng/L, obviously lower than before (967.04±366.16) ng/L(P<0.01) .before cardioversion,but plasma NT-pro BNP level of unsuccessful group was (1 182.04±298.34) ng/L,Compared with after medication for 48 hours(996.76±351. 28) ng/L,had no change!P <0.05). Conclusion Plasma NT-pro BNP level has forecast values for drug cardioversion effect in hospitalized patients with HF combined with AF.
Natriuretic Peptide, BrainmetabolismAtrial FibrillationcomplicationsHeart FailurecomplicationsAmiodaronetherapeutic use
NETL
NSTL
万方数据
维普
