Study on value and clinical application of prone position ventilation in acute respiratory distress syndrome
Objective To investigate the value and clinical application of prone position ventilation in acute respiratory distress syndrome(ARDS). Methods 36 cases of ARDS treated in our hospital from 2006 05 to 2010 06 months were randomly divided into two groups,one group was placed in the supine position with lung protective ventilation strategy as a control group,another group using the prone position of lung protective ventilation strategy for treatment of group. Monitoring of patients in the 2 groups were adequate sedation cases initial supine and prone position ventilation in 1 h,2 h,4 h,6 h in patients with arterial partial pressure of oxygen(PaO2) .oxygenation index(PaO2/ FiO2)pH, arterial partial pressure of carbon dioxide (PaCO2, SpO2), heart rate (HR), average arterial pressure (MAP) .central venous pressure(CVPl and other respiratory cycle index. Results The prone position group partial pressure of oxygen in arterial blood (PaO2), oxygenation index (PaO2/FiO2) ,SpO2 and other respiratory indicators were improved significantly than the control group(P<0. 05),mechanical ventilation time,duration of hospitalization and mortality during hospitalization were significantly reduced( P<0. 05). While the pH value,arterial partial pressure of carbon dioxide( PaCOi), heart rate( HR), mean arterial pressure (MAP), central venous pressure (CVP) .respiratory and circulatory indices compared with the control group had no significant difference (P>0.05). Conclusion The prone position ventilation can significantly improve the ARDS patient's oxygenation status,and restoring after oxygenation improved persistence. Prone position ventilation in acute respiratory distress syndrome (ARDS) therapy has good clinical application value.
Pulmonary Gas ExchangeProne PositionRespiratory Distress Syndrome, Adult
NETL
NSTL
万方数据
维普
