Significance of Urinary leukotriene E4, Immunoglobulin E and peripheral blood eosinophil count in predicting the prognosis of bronchiolitis
Objective To explore the significance of urinary leukotriene E4, immunoglobulin E and peripheral blood e-osinophil count in predicting the prognosis of bronchiolitis. Method To detect LTE, IgE and EC of 62 patients in the acute stage and convalescence, and 30 cases in the control group. 62 patients were divided into observation group and control group randomly, and the observation group were treated with Montelukast. Three months after discharge, the number of cases with wheeze outbreak was observed. Result LTE, and IgE of observation group were synchronous significantly increased in the acute stage and convalescence compared with control group (P<0. 01). There was no significant difference of EC between two groups(P>0. 05). The recurrence of observation group rate was lower significantly than that of control group. Conclusions LTE, and IgE were important inflammatory mediators in pathogenic process of capillary bronchitis and EC could not complete represent the airway inflammation. Oral Montelukast have effects in the early intervention,and can decrease morbidity of capillary bronchitis.
NETL
NSTL
万方数据
维普
