Objective To explore the plasma BNP (BNP) and amino-terminal type B urinary sodium peptide precursor (NT-proBNP) change and cardiac function in patients with vascular lesions of the relationship. Methods 108 cases of patients with cardiac insufficiency 2 weeks after venous serum in separation, 28 cases of patients with heart disease as a normal control group, the chemical luminescence method to determine the BNP and NT-proBNP. Results The control group, and cardiac function Ⅰ level group, Ⅱ level group, Ⅲ level group, Ⅳ plasma BNP levels level group were (51. 34±11. 27, 155.06±39.12, 247. 05±68. 34, 513.17±127. 88 (612. 34± 155. 87). NT-proBNP (μg/L) levels were (25. 78±14. 49, 177. 86±143. 65, 299. 81 ±166. 09, 608. 17±123. 14, 979. 04± 176. 45), comparative differences between groups are statistically significant (P<0. 01). Conclusion Plasma BNP levels rise and the severity of the coronary lesions, NT-proBNP can be used to evaluate the heart to contract early function is not complete, early evaluation diastolic dysfunction and ventricular segmental wall motion coordination.
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