Influence of Perilla oil in rats with breast cancer induced by dimethyl benzene anthracene
Objective To discuss the prevention role of Perilla oil in rats with breast cancer induced by dimethyl benzene anthracene. Methods Wistar rats were randomly divided into group A (control group) , tumor group B( induction application Perilla oil),before the group C(after induction application Perilla oil). One-time subcutaneous gived DMBA rats induced by breast cancer happen,observation model of induction of DMBA Perilla oil rat models of breast cancer tumor location and time of occurrence,tumor diameter,tumor-burdened quantity,rat growth situation. Results Perilla oil significantly suppressed rat breast cancer,delayed rat breast cancer incidence tumors,reduce time. Conclusion Perilla to DMBA oil induced rat breast cancer prevention role,its mechanism may for the effective ingredient;.basil oil α-linolenic acid enhance immune system rats tumor-burdened resistance,remove blood from the oxidative stress oxygen free radicals,inhibiting tumor cell proliferation.
Breast Neoplasmschemically induced9,10-Dimethyl-l,2-benzanthraceneadverse effectPerilla frutescenstherapeutic use