高血压伴颈部动脉粥样硬化的危险性分析
Analysis on fatalness of hypertension combined with carotid artery atherosclerosis
叶向 1杨洋 1时霞飞 1王宏俊 1龚元淑2
作者信息
- 1. 江苏省南京市浦口区中心医院心内科 211800
- 2. 江苏省南京市浦口区中心医院心超室 211800
- 折叠
摘要
目的 探讨高血压伴颈部动脉粥样硬化的危险性,及踝臂指数(ABI)、血脂Lp(a)在颈动脉粥样硬化预测中的作用.方法 选取2010-01-2011-06在南京市浦口区中心医院进行住院治疗的49例高血压患者作为研究对象.同时选取同期在我院进行住院的非高血压患者50例作为对照组.测量所有研究对象的裸臂指数、血脂Lp(a)和颈动脉内膜中层厚度.结果 高血压组的血脂、CRP和颈动脉厚度显著高于非高血压组,且两组差异均具有统计学意义(P＜0.05)；而ABI明显低于非高血压组,差异也具有统计学意义(P＜0.05).ABI≤1.0与ABI＞ 1.0的颈动脉内膜厚度分别为(0.93±0.16)mm和(0.76±0.19)mm,差异具有统计学意义(P＜0.05),而ABI≤1.0组的CRP显著低于ABI＞ 1.0组.结论 ABI值和血脂Lp(a)水平与高血压具有很强的相关性,并且具有检测简便,不需要特殊设备,值得在实际工作中推广应用.
Abstract
Objective To investigate the fatalness of hypertensive combined with carotid artery atherosclerosis, and the effect of ankle-brachial index (ABI) and blood lipid Lp(a) in the prediction of carotid atherosclerosis. Methods 49 patients with hypertension hospitalized in our hospital from 2010 January to 2011 June were enrolled in the study, while 50 non-hypertensive patients were selected hospitalized in our hospital as control group. Brachial index .blood lipid Lp(a) and carotid intima media thickness of all subjects were measured. Results The blood lipids and thickness of the carotid artery of hypertensive group were significantly higher than the non-hypertensive group,and the difference between two groups were statistically significant (P<0.05); and ABI significantly lower than non-hypertensive group,the difference was statistically significant(P<0. 05). The carotid artery intima-media thickness of ABI≤1.0 and ABI>1.0 group was(0. 93±0.16) mm and (0. 76±0.19) mm respectively. The difference was statistically sig-nificant(P<0.05) .indicating the correlation between lower ABI and carotid atherosclerosis. Conclusion There are strong correlation between ABI values,lipid Lp(a) levels and hypertension. The test is simple and does not require special equipment,and it is worth applicate widely in clinical practice.
关键词
高血压/并发症/颈动脉疾病/并发症Key words
Hypertension/complications/Carotid Artery Diseases/complications引用本文复制引用
出版年
2012
NETL
NSTL
维普
万方数据