The COx emissions of ship main engines should meet the relevant requirements of IMO.This paper conducts design and layout analysis based on methanol fuel power systems,and meanwhile studies specifically key issues such as the bunkering system and inerting monitoring function.The results show that the utilization of the U-typed enclosed top flat design can save space on the main deck and achieve self-flow on/off function.The analysis shows that PV valves set on the fuel tank,and dry gas purging(wind speed of 0.5~3.0 m/s)and combustible gas detec-tion installed on the valve outlet can effectively control fuel tank pressure and conduct inerting monitoring,with en-hanced system safety.