In order to reduce the weight of a marine hydraulic cylinder,this paper presents a design with mate-rial replacement and structure optimization.First of all,this paper replaced the material Q345B of the original struc-ture according to the statistics and sensitivity analysis.In addition,to reduce the weight of the hydraulic cylinder,under the constraints of material stress and cylinder deformation,this paper optimized the structure of the hydraulic cylinder by using the response surface optimization method based on central composite design(CCD).The analysis results show that under the condition of satisfying the wall thickness check,compared with the original structure,this design reduced the weight of the cylinder by about 4.83%,which provides a certain basis for the structural de-sign of the marine hydraulic cylinder in the later stage.