Nosocamial infection distribution and drug resistance of carbapenem-resistant Acinetobacter baumannii in intensive care unit and general ward
Objective To investigate the nosocomial infection,detection status and drug resistance of carbapenem-resistant Acinetobacter baumannii(CRAB)in intensive care units(ICU)and general wards.Methods The clinical data and microbial information of inpatients from January 2016 to December 2019 were retrospectively investigated,and the characteristics of CRAB infection and drug resistance in the two groups were analyzed.Results There were 305 cases of CRAB nosocomial infections,including 250 cases(1.69%)in ICU and 55 cases(0.02%)in general wards,and the infection sites were mainly lower respiratory tract.In ICU group,the incidence of CRAB infection cases in ventilator-associated pneumonia and bloodstream infection was higher,and the detection rate of CRAB infection was higher,showing a downward trend year by year.The drug resistance rate of CRAB to tigecycline was the lowest,followed by amikacin,and the drug resistance rate of CRAB to other commonly used antibiotics was more than 90%.The drug resistance rate of CRAB to tigecycline and tobramycin in general ward was higher than that in ICU.The drug resistance rate of carbapenem sensitive Acinetobacter baumannii to most commonly used antibiotics was mostly less than 10%.Conclusion There are some differences in the infection sites of CRAB,detection rate and drug resistance between ICU and general ward.We should strengthen the monitoring of CRAB infection,use drugs scientifically and rationally,and effectively control infection and slow down transmission.
intensive care unitgeneral wardcarbapenem-resistant Acinetobacter baumanniiinfection sitedrug resistance
NETL
NSTL
万方数据
维普
