首页|综合重症监护室住院患者多重耐药菌的临床分布特点及感染危险因素分析

综合重症监护室住院患者多重耐药菌的临床分布特点及感染危险因素分析

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目的 了解综合重症监护室(ICU)住院患者多重耐药菌(MDRO)的临床分布特点,分析感染危险因素.方法 回顾性调查2018年1月—2020年12月综合ICU病房3 406例患者MDRO感染情况及病原学特点,使用多因素logistic回归分析综合ICU住院患者MDRO感染危险因素.结果 该医院综合ICU 3年MDRO平均感染率为7.8%,264株(65.19%)来源于呼吸道.多因素logistic回归分析结果显示,性别、ICU住院天数≥14 d、肾脏疾病、机械通气、中心静脉导管插管、抗菌药物使用种类≥3、氨基糖苷类抗菌药物使用是ICU住院患者MDRO感染的独立危险因素.结论 ICU住院患者MDRO感染最常见的检出标本为呼吸道标本,多种因素为MDRO感染发生提供了有利条件.
Analysis of clinical distribution characteristics and infection risk factors of multi-drug resistant organism in ICU
Objective To understand the clinical distribution characteristics of multidrug resistant bacteria in general intensive care unit(ICU),to analyze the risk factors related to infection.Methods The MDRO infection and etiological characteristics of 3 406 patients in general ICU ward from January 2018 to December 2020 were analyzed through retrospective investigation.The risk factors of MDRO infection in ICU were analyzed by univariate and multivariate logistic regression.Results The three-year average infection rate of MDRO in the general ICU of the hospital was 7.8%.The infection trend and overall composition were stable.The main samples of MDRO came from the respiratory tract.The results of binary logistic regression analysis showed that gender,length of ICU stay≥14 d,renal disease,mechanical ventilation,central venous catheter,type of antibiotics≥3 and history of aminoglycoside antibiotics were independent risk factors of MDRO infection in the ICU.Conclusion MDRO infection in the general ICU is mainly from the respiratory tract.A variety of factors provide favorable conditions for the occurrence of MDRO infection.

intensive care unitmulti-drug resistant organismrisk factors

李孝雪、耿苗苗、祝延红

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上海交通大学公共卫生学院,上海 200001

上海交通大学附属第一人民医院

重症监护室 多重耐药菌 危险因素

国家自然科学基金

71974127

2024

中国消毒学杂志
军事医学科学院疾病预防控制所,中华预防医学会

中国消毒学杂志

CSTPCD
影响因子:0.754
ISSN:1001-7658
年,卷(期):2024.41(2)
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