首页|60Co-γ射线辐照灭菌对大豆异黄酮胶囊理化性状的影响与灭菌效果研究

60Co-γ射线辐照灭菌对大豆异黄酮胶囊理化性状的影响与灭菌效果研究

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目的 观察60Co-γ 射线辐照灭菌对大豆异黄酮胶囊的影响及灭菌效果.方法 采用微生物定量培养和理化分析方法,观察60Co-γ 射线灭菌对大豆异黄酮胶囊的影响及灭菌效果.结果 经过10 kGy 60Co-γ 辐照灭菌处理,大豆异黄酮胶囊的外观性状无变化,且崩解时限符合规定,3种主成分含量差异均无统计学意义(P>0.05),指纹图谱确认有14个共有峰,相似度≥0.999,色谱图无明显变化,大豆异黄酮胶囊中微生物明显减少.结论 60Co-γ 辐照灭菌对大豆异黄酮胶囊质量无显著影响,能有效降低大豆异黄酮胶囊微生物含量.
Sterilization effect of 60Co-γ-ray irradiation and its effect on physicochemical characters of soy isoflavones capsules
Objective To observe the sterilization efficacy and effectiveness of 60Co-γ irradiation sterilization on soy isoflavone capsules.Methods Microbial quantitative cultivation and physicochemical analysis methods were used to observe the effect of 60Co-γ radiation on quality of soy isoflavone capsules and sterilization efficacy.Results After treated with 60Co-γ-rays at 10 kGy,the appearance of soy isoflavone capsules exhibited no changes,and the disintegration time was up to the standards.There was no significant difference in the contents of three main components(P>0.05).There were 14 common peaks in chromatographic fingerprint with a similarity of≥0.999,and there were no significant difference in the chromatogram.Microorganisms in the irradiated soy isoflavone capsules significantly decreased.Conclusion 60Co-γ irradiation has no significant effect on the quality of soy isoflavone capsules and can effectly reduce the microorganisms in soy isoflavone capsules.

soy isoflavones capsules60Co-γirradiation sterilizationsterilization effect

李敏、龚亚、汪忠军、曹健

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中国人民解放军陆军军医大学第二附属医院,重庆 400037

大豆异黄酮胶囊 60Co-γ 辐照灭菌 灭菌效果

2024

中国消毒学杂志
军事医学科学院疾病预防控制所,中华预防医学会

中国消毒学杂志

CSTPCD
影响因子:0.754
ISSN:1001-7658
年,卷(期):2024.41(3)
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