Study on the antibacterial performance and influencing factors of a copper based nanomaterial
Objective To study the antibacterial performance of a copper-based nanomaterial and the factors affecting its antibacterial effect,and to explore the the possibility of its practical application.Methods The film pasting method was used to test the antibacterial performance of the copper-based nanomaterial against Staphylococcus aureus and Escherichia coli,and the effects of organic interference,temperature and humidity changes,chemical neutralization and other conditions on the antibacterial performance of the material were studied.Results The killing logarithmic values of Staphylococcus aureus and Escherichia coli on the surface of the copper-based nanomaterial were>6.71 and>6.37 respectively when the nanomaterial was treated at 37℃and a relative humidity of 90%humidity for 1 h.Using Staphylococcus aureus as the indicator bacterium,the killing logarithmic value decreased to 5.87 when 3%BSA was added;under the conditions of reducing temperature 20℃,90%and humidity 37℃,30%,the killing logarithmic values decreased to 2.78 and 3.59,respectively;after using D/E neutralizer,the killing logarithmic value decreased to 4.15.Conclusion This copper-based nanomaterial has good antibacterial performance,but organic interference and changes in environmental temperature and humidity can affect its bactericidal effect,and the use of neutralizers during evaluation will also directly affect the test results.
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