Analysis of prognostic risk factors for carbapenem resistant Enterobacteriaceae infection in hospitalized patients
Objective To investigate the prognostic factors of carbapenem resistant Enterobacteriaceae(CRE)infection in hospitalized patients.Methods Through pathogen specimen isolation and identification and antimicrobial susceptibility testing,the prognostic risk factors of hospital acquired CRE infection among hospitalized patients in a hospital were statistically analyzed.Results A total of 135 patients with CRE infection were investigated and analyzed.CRE was mainly isolated from lower respiratory tract secretions,accounting for 57.04%.The resistance rate of clinically isolated CRE strains to cephalosporin antibiotics exceeded 70%,and the resistance rate to ampicillin sulbactam and tobramycin reached 50%to 80%.Multivariate analysis showed that factors such as platelet count,bilirubin levels,complicated with cardiovascular and cerebrovascular diseases,multiple organ dysfunction syndrome,and gastric tube intubation were independent prognostic risk factors for patients with CRE infection.Conclusion The main site of CRE infection is the lower respiratory tract in this hospital,and the risk factors affecting patient prognosis are clear.Targeted prevention and control measures should be developed.