Distribution and drug resistance analysis of clinical isolates of Enterobacter
Objective To investigate the clinical distribution and drug resistance of Enterobacter in nosocomial infection.Methods Bacteriological examination and antimicrobial susceptibility test were used to detect and analyze the pathogenic specimens of nosocomial infection patients in a hospital.Results A total of 971 strains of Enterobacter were detected,mainly isolated from sputum and urine samples.Among the 971 strains of Enterobacter,Enterobacter cloacae and Enterobacter aerogenes accounted for 55.72%and 41.10%,respectively.Enterobacter cloacae and Enterobacter aerogenes were 100%resistant to cefazolin,ampicillin,ampicillin/sulbactam,and cefotetan.Enterobacteriaceae were sensitive to carbapenems,third-generation cephalosporins,aminoglycosides,and vanolone antimicrobials.Conclusion The clinical isolates of Enterobacteriaceae in patients with nosocomial infection in a hospital are mainly Cloacillus and Enterobacter aerogenes,which are seriously resistant to some antimicrobial drugs such as cefazolin,and are sensitive to carbapenems and third-generation cephalosporins.